Trifluoroacetic acid → 2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-B]pyridine

HRID 225533Notes

Reaction equation

HRID 225533 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]2[CH2:8][N:9](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[CH2:10][C:5]2=[CH:4][CH:3]=1.FC(F)(F)C(O)=O>>[Cl:1][C:2]1[N:7]=[C:6]2[CH2:8][NH:9][CH2:10][C:5]2=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 577532782-Chloro-6-trityl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine

Product 1

HCID 113671312-Chloro-6,7-dihydro-5H-pyrrolo[3,4-B]pyridine

Procedure

Prepared in analogy to Example A2(c) from 2-chloro-6-trityl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine and trifluoroacetic acid. Light brown solid. MS (m/e): 154.9 ([M+, 100%).

Sources & evidence

ORD record
ord-5b9cbe1561424879a18839b40860b92a
Source dataset
uspto-grants-2009_07
Patent number
US07557114B2

Reaction notes

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