HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 19738050, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-Chlorobenzyl cyanide | HCID 241582 | — |
| Reactant | 4-(3-Chloropropyl)-2,6-dimethylmorpholine | HCID 19738017 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 19738050 | HCID 19738050 | — |
Reaction Steps
This intermediate (2.0 g.) was prepared using the procedure described in Example 2a except using 2.3 g. (11 moles) of 4-(3-chloropropyl)-2,6-dimethylmorpholine, 0.48 g. of sodium hydride, and 1.69 g. (11 mmoles) of 4-chlorobenzyl cyanide in 15 ml. of a 2 to 1 mixture of toluene and DMF and was isolated as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05240925 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-78d7f8d414b24a0c95ca254035ff6810 |
| Source note | uspto-grants-1993_08 |