HCID 12880746, compound → Ethyl Acrylate

HRID 2255414Notes

Reaction equation

HRID 2255414 reaction equation
Cl.[CH2:2]([C:4]1[CH:9]2[CH2:10][CH:11]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[CH:6]([N:7]([CH2:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[CH:8]2[CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:5]=1)[CH3:3]>C1(C)C=CC=CC=1>[C:25]1([CH2:24][N:7]2[CH:6]=[CH:5][C:4]([CH2:2][CH3:3])=[CH:9][CH:8]2[CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1.[C:12]([O:14][CH2:15][CH3:16])(=[O:13])[CH:11]=[CH2:10]

Participants

4

Reactant 1

HCID 12880746HCID 12880746, compound

Product 2

HCID 8821Ethyl AcrylateYield 451.8%HCID 19738111HCID 19738111, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Following a procedure similar to that described in Example 1(c), 132 g (44%) of ethyl 8-ethyl-2,3-di(phenylmethyl)-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylate hydrochloride, m.p. 197°-200° C., was obtained from 1,2-dihydro-N,2-di(phenylmethyl)-4-ethylpyridine of Example 3(b), toluene (1400 mL) and ethyl acrylate (154 mL, 1.4 mol).

Sources & evidence

ORD record
ord-49a2c9e69ce74dd294dba45713baa379
Source dataset
uspto-grants-1993_08
Patent number
US05240935

Reaction notes

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