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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2255463Generated: October 27, 2026

Glycine ethyl ester → N-(2-amino-3,4-dioxo-1-cyclobutenyl)glycine ethyl ester

https://huagongshe.com/reaction/2255463

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycine ethyl esterHCID 12176—
Reactant3-Amino-4-ethoxycyclobut-3-ene-1,2-dioneHCID 15146336—
ProductN-(2-amino-3,4-dioxo-1-cyclobutenyl)glycine ethyl esterHCID 10035618—

Reaction Steps

In the same manner, condensing stoichiometric amounts of 3-amino-4-ethoxy-3-cyclobutene-1,2-dione with ethyl glycinate produces N-(2-amino-3,4-dioxo-1-cyclobutenyl)glycine ethyl ester, m.p. 231°-233° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05240946
Source datasetuspto-grants-1993_08
ORD IDord-13890d683aef49c5a1c7d4741b6aa157
Source noteuspto-grants-1993_08