HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropyl Ether → HCID 14668279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropyl Ether | HCID 7914 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (S)-(-)-2-Aminomethyl-1-ethylpyrrolidine | HCID 643457 | — |
| Reactant | HCID 14668268 | HCID 14668268 | — |
| Product | HCID 14668279 | HCID 14668279 | — |
Reaction Steps
3-Propyl-2,5,6-trimethoxybenzoic acid (23 g, 0.09 mol) was treated with thionyl chloride and (2S)-(-)-1-ethyl-2-aminomethylpyrrolidine as described in example 4. Yield 10.6 g (32%). M.p. 68°-70° C. (i-Pr2O). 1H-NMR (CDCl3): δ6.73 (s,1H), 6.40 (b,1H), 3.85 (Sx2,6H), 3.76 (s,3H), 0.9-3.8 (m,21H)ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05240957 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-26b8dbcc716a44918e937560b2cb10fc |
| Source note | uspto-grants-1993_08 |