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HRID2255515

反应详情

EQUATION

反应方程式

HRID 2255515 的结构方程式

REACTANTS

反应物

4
结构：CC(C)OC(C)C
HCID7914

Isopropyl ether

C6H14O

结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：CCN1CCC[C@H]1CN
HCID643457

1-[(2S)-1-Ethylpyrrolidin-2-yl]methanamine

C7H16N2

结构：CCCc1cc(OC)c(OC)c(C(=O)O)c1OC
HCID14668268

未命名化合物

PRODUCTS

生成物

1
结构：CCCc1cc(OC)c(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1OC
HCID14668279

未命名化合物

PROCEDURE

实验过程

3-Propyl-2,5,6-trimethoxybenzoic acid (23 g, 0.09 mol) was treated with thionyl chloride and (2S)-(-)-1-ethyl-2-aminomethylpyrrolidine as described in example 4. Yield 10.6 g (32%). M.p. 68°-70° C. (i-Pr2O). 1H-NMR (CDCl3): δ6.73 (s,1H), 6.40 (b,1H), 3.85 (Sx2,6H), 3.76 (s,3H), 0.9-3.8 (m,21H)ppm.