Trifluoroacetic acid → HCID 57753638, compound

HRID 225555Notes

Reaction equation

[F:1][C:2]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[C:7]2[C:3]=1[CH2:4][N:5](C(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[CH2:6]2.FC(F)(F)C(O)=O>>[F:1][C:2]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[C:7]2[C:3]=1[CH2:4][NH:5][CH2:6]2

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 57753565HCID 57753565, compound

Product 1

HCID 57753638HCID 57753638, compound

Procedure

Prepared in analogy to Example A2(c) from 4-Fluoro-6-trifluoromethyl-2-trityl-2,3-dihydro-1H-isoindole and trifluoroacetic acid. Yellow oil. MS (m/e): 206.1 ([M+H+, 100%).

Sources & evidence

ORD record: ord-f286c0494cd2438bb3e7e0291c23851d
Source dataset: uspto-grants-2009_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07557114B2

Reaction notes

Loading…