HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 19385744, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 2-Hydroxy-5-methylacetophenone | HCID 15068 | — |
| Reactant | Methyl 2-(2-bromophenyl)acetate | HCID 8063364 | — |
| Reactant | Acetone potassium carbonate | HCID 86600397 | — |
| Product | HCID 19385744 | HCID 19385744 | 63% |
Reaction Steps
Using the K2CO3 /acetone conditions for phenol alkylation described in Step A of Example 30, 1.00 g (6.67 mmol) of 2'-hydroxy-5'-methylacetophenone was alkylated with 1.68 g (7.34 mmol) of methyl 2-bromophenylacetate to afford 1.25 g (63%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05240938 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-71c7bd7b93774bdbad846a91b869a246 |
| Source note | uspto-grants-1993_08 |