Barium Carbonate → HCID 16228711, compound

HRID 2255710Notes

Reaction equation

HRID 2255710 reaction equation
[N:1]12[CH2:11][S:10][CH2:9][CH:8]1[CH2:7][CH:6]1[CH:2]2[CH2:3][N:4](C(OCC)=O)[CH2:5]1.C(=O)([O-])[O-].[K+].[K+].C(=O)([O-])[O-].[Ba+2]>O>[N:1]12[CH2:11][S:10][CH2:9][CH:8]1[CH2:7][CH:6]1[CH:2]2[CH2:3][NH:4][CH2:5]1

Participants

5

Reactant 3

HCID 10563Barium CarbonateHCID 11430Potassium CarbonateHCID 54120114HCID 54120114, compound

Product 1

HCID 16228711HCID 16228711, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

12.5 g (50 mmol) of ethyl 10-thia-1,4-diazatricyclo[6.3.0.02,6 ]undecane-4-carboxylate are heated under reflux overnight with 32 g of Ba(OH)2.8H2O in 225 ml of water. Potassium carbonate is added to the mixture, barium carbonate is filtered off with suction and the filtrate is extracted ten times using 100 ml of chloroform each time. The extracts are dried over potassium carbonate and concentrated, and the residue is distilled.

Workup

  1. filtrationis filtered off with suction
  2. extractionthe filtrate is extracted ten times
  3. dry with materialThe extracts are dried over potassium carbonate
  4. concentrationconcentrated
  5. distillationthe residue is distilled

Sources & evidence

ORD record
ord-c01c39ff0b91467282b2bd2e7456c10e
Source dataset
uspto-grants-1993_08
Patent number
US05241076

Reaction notes

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