反应详情

7.8 g (36 mmol) of 2-benzyl-8-methyl-2,7-diazabicyclo[3.3.0]octane in 200 ml of ethanol are hydrogenated at 100° C. and 100 bar on 2 g of palladium-active carbon (10% Pd). The catalyst is filtered off with suction, the filtrate is concentrated and the residue is distilled. The distillate crystallizes.

1. customare hydrogenated at 100° C.
2. filtrationThe catalyst is filtered off with suction
3. concentrationthe filtrate is concentrated
4. distillationthe residue is distilled