Octahydro-6-methyl-1-(phenylmethyl)pyrrolo[3,4-b]pyrrole → HCID 22924398, compound

Participants

Reaction Steps

7.8 g (36 mmol) of 2-benzyl-8-methyl-2,7-diazabicyclo[3.3.0]octane in 200 ml of ethanol are hydrogenated at 100° C. and 100 bar on 2 g of palladium-active carbon (10% Pd). The catalyst is filtered off with suction, the filtrate is concentrated and the residue is distilled. The distillate crystallizes.

Provenance & Evidence