Ethanol → HCID 22924376, compound

HRID 2255718Notes

Reaction equation

HRID 2255718 reaction equation
C([N:8]1[CH2:15][CH2:14][CH:13]2[CH:9]1[CH2:10][NH:11][CH2:12]2)C1C=CC=CC=1.[CH2:16](O)[CH3:17]>[Pd]>[CH3:10][N:11]1[CH:16]([CH3:17])[CH:9]2[CH:13]([CH2:14][CH2:15][NH:8]2)[CH2:12]1

Participants

4

Reactant 2

HCID 702EthanolHCID 225622081-Benzyloctahydropyrrolo[3,4-b]pyrrole

Product 1

HCID 22924376HCID 22924376, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

10.8 g (46.9 mmol) of 2-benzyl-2,7-diazabicyclo[3.3.0]octane in 200 ml of ethanol are hydrogenated at 100° C. and 100 bar on 2.5 g of palladium-active carbon. The catalyst is filtered off with suction, the filtrate is concentrated and the residue is distilled.

Workup

  1. customare hydrogenated at 100° C.
  2. filtrationThe catalyst is filtered off with suction
  3. concentrationthe filtrate is concentrated
  4. distillationthe residue is distilled

Sources & evidence

ORD record
ord-5883218f06ef42fe9c6578b14153a730
Source dataset
uspto-grants-1993_08
Patent number
US05241076

Reaction notes

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