Aminoacetaldehyde dimethyl acetal → HCID 54527212, compound

Temperature

0 °C

200 g of molecular sieve are initially introduced into 1,000 ml of ethanol and 105 g (1 mol) of aminoacetaldehyde dimethyl acetal and 70 g (1 mol) of crotonaldehyde are added. The mixture is allowed to stand at room temperature overnight, decanted off from molecular sieve and cooled to 0° C., and 40 g of sodium borohydride are added in 1 g portions. The mixture is then stirred overnight at room temperature and concentrated, the residue is taken up in 500 ml of water and potassium carbonate is added until an organic phase separates. This is extracted using chloroform, dried over potassium carbonate and concentrated, and the residue is distilled.

1. additionare added
2. customdecanted off from molecular sieve
3. addition40 g of sodium borohydride are added in 1 g portions
4. concentrationconcentrated
5. additionpotassium carbonate is added until an organic phase separates
6. extractionThis is extracted
7. dry with materialdried over potassium carbonate
8. concentrationconcentrated
9. distillationthe residue is distilled

ORD record

ord-7e53565217e14f95af9a59c39f335d56

Source dataset

uspto-grants-1993_08

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05241076