Water → HCID 19738537, compound

HRID 2255726Notes

Reaction equation

HRID 2255726 reaction equation
Cl[CH:2]([CH3:5])[CH:3]=[CH2:4].[CH3:6][O:7][CH:8]([O:16][CH3:17])[CH2:9][NH:10][C:11](=[O:15])[O:12][CH2:13][CH3:14].[OH-].[K+].O>CN(C)C=O>[CH2:4]=[CH:3][CH:2]([N:10]([CH2:9][CH:8]([O:7][CH3:6])[O:16][CH3:17])[C:11](=[O:15])[O:12][CH2:13][CH3:14])[CH3:5]

Participants

6

Reactant 4

HCID 962WaterHCID 112423-Chloro-1-buteneHCID 14797Potassium HydroxideHCID 10921057Ethyl 2,2-dimethoxyethylcarbamate

Product 1

HCID 19738537HCID 19738537, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

22 g (0.24 mol) of 3-chloro-1-butene are added to 35.5 g (0.2 mol) of ethyl N-(2,2-dimethoxyethyl)-carbamate and 26 g of powdered potassium hydroxide in 400 ml of dimethylformamide and the mixture is warmed overnight to 40° C. The salts are dissolved with water and the mixture is extracted several times with methylene chloride. The organic extracts are dried over potassium carbonate and concentrated, and the residue is distilled.

Workup

  1. temperaturethe mixture is warmed overnight to 40° C
  2. extractionthe mixture is extracted several times with methylene chloride
  3. dry with materialThe organic extracts are dried over potassium carbonate
  4. concentrationconcentrated
  5. distillationthe residue is distilled

Sources & evidence

ORD record
ord-c3f98e08b73c470b91315429a00fe978
Source dataset
uspto-grants-1993_08
Patent number
US05241076

Reaction notes

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