Ethyl cyanoacetate → HCID 338194, compound

HRID 2255794Notes

Reaction equation

HRID 2255794 reaction equation
COS([O-])(=O)=O.N1([NH+]=[C:13]([N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)N)CCCC1.[C:20]([CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])#[N:21].[OH-].[Na+]>C1(C)C=CC=CC=1>[N:15]1([CH:13]=[C:22]([C:20]#[N:21])[C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

5

Reactant 3

HCID 7764Ethyl cyanoacetateHCID 14798Sodium HydroxideHCID 178503015HCID 178503015, compound

Product 1

HCID 338194HCID 338194, compoundYield 95.5%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Analogously to Example 1, 27.6 g of 95.5% pure dipyrroli-dino-formamidinium methylsulphate were reacted with 11.4 g of ethyl cyanoacetate and 4.0 g of NaOH powder in 140 ml of toluene. After work-up, 95.5% of ethyl pyrrolidino-methylenecyanoacetate were obtained.

Sources & evidence

ORD record
ord-fde892dfad6d46d0a0d77a1a2c323d3d
Source dataset
uspto-grants-1993_08
Patent number
US05241099

Reaction notes

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