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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225580Generated: October 26, 2026

2-Methoxyethanol → 5-(2-Methoxy-ethoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/225580

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyethanolHCID 8019—
Reactanttert-Butyl 5-iodoisoindoline-2-carboxylateHCID 57753580—
Product5-(2-Methoxy-ethoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753559—

Reaction Steps

Prepared in analogy to Example A6(a) from 5-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and 2-methoxyethanol. White solid. MS (m/e): 237.9 ([M+H−Me2C═CH2]+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-f5013b1dea8f4c2e992c87e8ea69f1df
Source noteuspto-grants-2009_07