Hydrochloric Acid → 5-(2-Methoxy-ethoxy)-2,3-dihydro-1H-isoindole hydrochloride

HRID 225581Notes

Reaction equation

HRID 225581 reaction equation
C(OC([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([O:17][CH2:18][CH2:19][O:20][CH3:21])[CH:14]=2)[CH2:9]1)=O)(C)(C)C.[ClH:22]>>[ClH:22].[CH3:21][O:20][CH2:19][CH2:18][O:17][C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][CH:12]=1)[CH2:9][NH:8][CH2:16]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 577535595-(2-Methoxy-ethoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

Product 1

HCID 688259185-(2-Methoxy-ethoxy)-2,3-dihydro-1H-isoindole hydrochloride

Procedure

Prepared in analogy to Example A3(e) from 5-(2-methoxy-ethoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. White solid. MS (m/e): 194.3 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-ad29da52d47245e2932725c7e574cf39
Source dataset
uspto-grants-2009_07
Patent number
US07557114B2

Reaction notes

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