HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Iodopropane → 2-(Propylthio)pyrimidine-4,6-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | HCID 178516656 | HCID 178516656 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | 2-(Propylthio)pyrimidine-4,6-diol | HCID 178460810 | — |
Reaction Steps
To a solution of 4,6-dihydroxy-2-mercaptopyrimidine (100 g) in potassium hydroxide (2.5N, 571 ml) was added propyl iodide (76.8 ml) and the whole was stirred for 4 days. The solution was acidified to pH 2-3 and filtered to afford the sub-title compound (15 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05654285 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-c39d40f5d3564ea99a87b7a10abbfef6 |
| Source note | uspto-grants-1997_08 |