Hydrochloric Acid → HCID 68822118, compound

HRID 225590Notes

Reaction equation

HRID 225590 reaction equation
C(OC([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][C:12]([C:20]([F:23])([F:22])[F:21])=[C:13]([O:17][CH2:18][CH3:19])[CH:14]=2)[CH2:9]1)=O)(C)(C)C.[ClH:24]>>[ClH:24].[CH2:18]([O:17][C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][C:12]=1[C:20]([F:23])([F:21])[F:22])[CH2:9][NH:8][CH2:16]2)[CH3:19]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 57753586HCID 57753586, compound

Product 1

HCID 68822118HCID 68822118, compound

Procedure

Prepared in analogy to Example A3(e) from 5-ethoxy-6-trifluoromethyl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. White solid. MS (m/e): 232.1 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-37e6e906517b48d5b8b95087350ef676
Source dataset
uspto-grants-2009_07
Patent number
US07557114B2

Reaction notes

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