Hydrochloric Acid → HCID 68821957, compound

HRID 225608Notes

Reaction equation

HRID 225608 reaction equation
C(OC([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([N:17]3[CH2:22][CH2:21][CH2:20][C:19]([F:24])([F:23])[CH2:18]3)[CH:14]=2)[CH2:9]1)=O)(C)(C)C.[ClH:25]>>[ClH:25].[F:24][C:19]1([F:23])[CH2:20][CH2:21][CH2:22][N:17]([C:13]2[CH:14]=[C:15]3[C:10](=[CH:11][CH:12]=2)[CH2:9][NH:8][CH2:16]3)[CH2:18]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 577536445-(3,3-Difluoro-piperidin-1-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

Product 1

HCID 68821957HCID 68821957, compound

Procedure

Prepared in analogy to Example A3(e) from 5-(3,3-difluoro-piperidin-1-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. Brown solid. MS (m/e): 239.3 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-1ede9e5bbb2840e893ecd1468fafdeca
Source dataset
uspto-grants-2009_07
Patent number
US07557114B2

Reaction notes

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