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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225612Generated: October 29, 2026

Hydrochloric Acid → 5-Methyl-6-morpholin-4-yl-2,3-dihydro-1H-isoindole hydrochloride

https://huagongshe.com/reaction/225612

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Methyl-6-morpholin-4-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl EsterHCID 57753377—
Product5-Methyl-6-morpholin-4-yl-2,3-dihydro-1H-isoindole hydrochlorideHCID 68822826—

Reaction Steps

Prepared in analogy to Example A3(e) from 5-methyl-6-morpholin-4-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. Brown solid. MS (m/e): 219.3 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-bc1313b18a66428083130e92c47740f2
Source noteuspto-grants-2009_07