HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | N-(3-bromophenyl)-6-fluoropyrido[3,4-d]pyrimidin-4-amine | HCID 5328260 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine | HCID 5328261 | — |
Reaction Steps
Treatment of 4-(3-bromoanilino)-6-fluoropyrido[3,4-d]pyrimidine (see a previous experimental) at 100° C. in a pressure vessel with piperidine in ethanol gives 4-(3-bromoanilino)-6-dimethylaminopyrido[3,4-d]pyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05654307 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-32d52bf1d2b8467e978b40f466acb6ad |
| Source note | uspto-grants-1997_08 |