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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225626Generated: October 29, 2026

Trifluoroacetic acid → 5-Cyclopropyl-6-morpholin-4-yl-2,3-dihydro-1H-isoindole trifluoroacetate

https://huagongshe.com/reaction/225626

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant5-Cyclopropyl-6-morpholin-4-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753370—
Product5-Cyclopropyl-6-morpholin-4-yl-2,3-dihydro-1H-isoindole trifluoroacetateHCID 68821896—

Reaction Steps

Prepared in analogy to Example A2(c) from 5-cyclopropyl-6-morpholin-4-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and trifluoroacetic acid. Brown solid. MS (m/e): 245.4 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-d21c596f3487448aa689b62ccf333f11
Source noteuspto-grants-2009_07