Hydrochloric Acid → HCID 131717326, compound

HRID 2256639Notes

Reaction equation

HRID 2256639 reaction equation
[CH2:1]([N:3](C(OC(C)(C)C)=O)[CH2:4][CH2:5][CH2:6][N:7](C(OC(C)(C)C)=O)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][N:16](C(OC(C)(C)C)=O)[CH2:17][CH2:18][CH2:19][N:20]([CH2:28][CH3:29])C(OC(C)(C)C)=[O:22])[CH3:2].[ClH:51]>C(O)C.C(OCC)C>[OH2:22].[ClH:51].[ClH:51].[ClH:51].[ClH:51].[CH2:28]([NH:20][CH2:19][CH2:18][CH2:17][NH:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][NH:7][CH2:6][CH2:5][CH2:4][NH:3][CH2:1][CH3:2])[CH3:29].[CH2:28]([NH:20][CH2:19][CH2:18][CH2:17][NH:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][NH:7][CH2:6][CH2:5][CH2:4][NH:3][CH2:1][CH3:2])[CH3:29].[ClH:51].[ClH:51].[ClH:51].[ClH:51]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 19030154HCID 19030154, compound

Product 1

HCID 131717326HCID 131717326, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 3283Diethyl EtherSolvent

Procedure

Dissolve 3.3 g (0.0046 mol) of the product of Step A in 7 ml ethanol and treat with 70 ml of 2N HCl in diethyl ether stirring overnight. Filter the mixture and dry the residue at 70° C. at reduced pressure to yield 1.95 g of the title compound, mp>300° C. Elemental analysis: Calculated, C-46.09, H-10.10, N-11.95, Cl-30.24; Found C-46.23, H-9.94, N-12.11, Cl-29.99.

Workup

  1. filtrationFilter the mixture
  2. customdry the residue at 70° C. at reduced pressure

Sources & evidence

ORD record
ord-f0a630f53dc14fdcad9a1ac7b49ef464
Source dataset
uspto-grants-1997_08
Patent number
US05654484

Reaction notes

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