HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Tributylstannyl-3,6-dihydro-2H-pyran → 2-Benzhydryl-5-(3,6-dihydro-2H-pyran-4-yl)-6-fluoro-2,3-dihydro-1H-isoindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Tributylstannyl-3,6-dihydro-2H-pyran | HCID 22252258 | — |
| Reactant | HCID 57753282 | HCID 57753282 | — |
| Product | 2-Benzhydryl-5-(3,6-dihydro-2H-pyran-4-yl)-6-fluoro-2,3-dihydro-1H-isoindole | HCID 57753239 | — |
Reaction Steps
Prepared in analogy to Example A49(a) from 2-benzhydryl-5-fluoro-6-iodo-2,3-dihydro-1H-isoindole and tributyl-(3,6-dihydro-2H-pyran-4-yl)-stannane. Yellow solid. MS (m/e): 386.1 ([M+H]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557114B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-f5c190cfadf04625a30962417b547de6 |
| Source note | uspto-grants-2009_07 |