Hydrochloric Acid → 1-Ethoxy-3-chloro-3-methyl-2-nitrosobutane

Participants

Reaction Conditions

Reaction Steps

Concentrated HCl was added to a cooled (0°-5° C.) solution of isoamyl nitrite (14.0 g, 120 mmol) and 1-ethoxy-3-methyl-2-butene (6.84 g, 60 mmol). The temperature was maintained below 5° C. during the addition and the reaction mixture was stirred at 5° C. for an additional 30 min. The product was filtered and washed with a cold (-20° C.) 1:1 mixture of ethanol and ether. The solid was further washed with ether to afford a white solid.

Provenance & Evidence