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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225681Generated: October 31, 2026

Cyclopropanemethanol → 5-Cyclopropylmethoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/225681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanolHCID 75644—
Reactanttert-Butyl 5-iodoisoindoline-2-carboxylateHCID 57753580—
Product5-Cyclopropylmethoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753275—

Reaction Steps

Prepared in analogy to Example A6(a) from 5-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A38(b)) and cyclopropylmethanol. Off-white solid. MS (m/e): 234.1 ([M+H-Me2C═CH2]+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-69df966797aa4ee9bc4a785468f48e19
Source noteuspto-grants-2009_07