Water → HCID 54395198, compound

HRID 2257096Notes

Reaction equation

HRID 2257096 reaction equation
[N+:1]([C:4]1[CH:10]=[C:9]([S:11][C:12]([F:15])([F:14])[F:13])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-:3])=[O:2].[Br:16]Br.O>FC(F)(F)C(O)=O.ClCCl>[Br:16][C:7]1[C:5]([NH2:6])=[C:4]([N+:1]([O-:3])=[O:2])[CH:10]=[C:9]([S:11][C:12]([F:15])([F:13])[F:14])[CH:8]=1

Participants

6

Reactant 3

HCID 962WaterHCID 24408BromineHCID 23279174HCID 23279174, compound

Product 1

HCID 54395198HCID 54395198, compound

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 6422Trifluoroacetic acidSolvent

Procedure

24 g of finely pulverulent 2-nitro-4-trifluoromethylmercaptoaniline were dissolved in 50 ml of tri-fluoroacetic acid, and 18 g of bromine were metered in at 20° C. Stirring was then continued for 3 hours at 20° C. and for a further 30 minutes at 40° C. The mixture poured into water and the product taken up in dichloromethane. After the solvent had been removed, 31 g of 6-bromo-2-nitro-4-trifluoromethylmercaptoaniline were obtained.

Workup

  1. customwere metered in at 20° C
  2. customAfter the solvent had been removed

Sources & evidence

ORD record
ord-cbe9d0ad025a437cbcc1259d4ef40605
Source dataset
uspto-grants-1997_08
Patent number
US05656649

Reaction notes

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