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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225724Generated: November 1, 2026

1,1,1-Trifluorobutan-2-ol → 5-Methanesulfonyl-2-(1-trifluoromethyl-propoxy)-benzoic acid

https://huagongshe.com/reaction/225724

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,1-Trifluorobutan-2-olHCID 11332471—
Reactant2-Fluoro-5-methanesulfonyl-benzoic acidHCID 22467566—
Product5-Methanesulfonyl-2-(1-trifluoromethyl-propoxy)-benzoic acidHCID 21100302—

Reaction Steps

Prepared in analogy to Example B4(c) from 2-Fluoro-5-methanesulfonyl-benzoic acid (example B4(b)) and rac-1,1,1-Trifluoro-butan-2-ol (CAS: 431-36-7). White solid. MS (m/e): 325.0 ([M−H], 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-d94fceeda7da494e95df3e4005a99937
Source noteuspto-grants-2009_07