HCID 131720114, compound → HCID 131720113, compound

HRID 2257242Notes

Reaction equation

HRID 2257242 reaction equation
[Li+:1].[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([O:16]C1COCCO1)([C:13]([OH:15])=[O:14])[C:10]([O-:12])=[O:11]>CO.CO.O>[Li+:1].[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:16])([C:10]([OH:12])=[O:11])[C:13]([O-:15])=[O:14]

Participants

4

Reactant 1

HCID 131720114HCID 131720114, compound

Product 1

HCID 131720113HCID 131720113, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 22242641Methanol--water (1/1)Solvent

Procedure

A solution of 0.69 g of said compound in 12 ml of MeOH is hydrolysed at r.t. with 9.3 ml of the LiOH in MeOH-H2O solution, to give 0.4 g of 3-(pyrid-2-yl)-2-hydroxy-2-carboxypropanoic acid lithium salt, m.p. >300° C., I.R (nujol) 3400, 1640 cm-1HNMR (D2O) δ (TMS): 3.4 S, 7.2-7.35 m, 7.65-7.8 m, 6.3-8.4 m.

Sources & evidence

ORD record
ord-ccb223464d4a4b8d947ac0a98031ec0f
Source dataset
uspto-grants-1997_08
Patent number
US05656656

Reaction notes

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