HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (R)-8-Fluoro-5-hydroxy-3-(N-3-pentyl-N-n-propylamino)chroman hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 53847727 | HCID 53847727 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (R)-8-Fluoro-5-hydroxy-3-(N-3-pentyl-N-n-propylamino)chroman hydrochloride | HCID 67703430 | — |
Reaction Steps
(R)-8-Fluoro-5-hydroxy-3-(N-3-pentyl-N-n-propylamino)chroman (180 mg, 0.6 mmol) was dissolved in ether. HCl in ether was added to precipitate the HCl-salt, and gave after drying 200 mg of (R)-8-fluoro-5-hydroxy-3-(N-3-pentyl-N-n-propylamino)chroman hydrochloride as a white powder. Mp: 80°-100° C. (sinters).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05656657 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-27070449cdf743a39194330a23c37fff |
| Source note | uspto-grants-1997_08 |