Trifluoroacetic acid → HCID 19028301, compound

HRID 2257415Notes

Reaction equation

HRID 2257415 reaction equation
[C:1]([N:8](C)[CH2:9][C:10]1[C:11]([CH2:16][N:17](C)[C:18](OC(C)(C)C)=O)=[CH:12][CH:13]=[CH:14][CH:15]=1)(OC(C)(C)C)=O.[F:27][C:28]([F:33])([F:32])[C:29]([OH:31])=[O:30]>ClCCl>[F:27][C:28]([F:33])([F:32])[C:29]([OH:31])=[O:30].[F:27][C:28]([F:33])([F:32])[C:29]([OH:31])=[O:30].[CH3:18][NH:17][CH2:16][C:11]1[C:10]([CH2:9][NH:8][CH3:1])=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 70255896HCID 70255896, compound

Product 1

HCID 19028301HCID 19028301, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Representative Procedure I: A solution of this crude N,N'-bis(Boc)-bis(methyl)xylylenediamine in 50% trifluoroacetic acid in dichloromethane (10 mL) was stirred at 23° C. for 0.5 h. The brown solution was concentrated. Diethyl ether was added to the residue, and the mixture was concentrated. The residue obtained was washed with diethyl ether (two portions), providing the N,N'-bis(methyl)-xylylene diamine bis(trifluoroacetate) as a yellow solid.

Workup

  1. concentrationThe brown solution was concentrated
  2. additionDiethyl ether was added to the residue
  3. concentrationthe mixture was concentrated
  4. customThe residue obtained
  5. washwas washed with diethyl ether (two portions)

Sources & evidence

ORD record
ord-4cdeddd423d84bddb8852ab1b1aec1e6
Source dataset
uspto-grants-1997_08
Patent number
US05656660

Reaction notes

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