Benzaldehyde → HCID 69061886, compound

Participants

Reaction Steps

Formula I where U—V is —CReRf—CRgRh—N(R6)—; R1, R4, Rb and Rc to Rh are H; R2 and R3 are methoxy; R5 is methyl; and Ra is phenethyl; and R6 is benzyl: By following the procedure described in Example 3, substituting 3-benzyl-7-chloro-1-(pyrrolidine-2-carbonyl)-2,3-dihydro-1H-quinazoline-4-one with 6,7-dimethoxy-2-[3-phenethyl-piperidin-4-yl]-3-methyl-3H-quinazolin-4-one, and substituting p-tolualdehyde with benzaldehyde, there is obtained 6,7-dimethoxy-2-[1-benzyl-3-phenethyl-piperidin4-yl]-3-methyl-3H-quinazolin-4-one.

Provenance & Evidence