Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | HCID 22923693 | HCID 22923693 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22923678 | HCID 22923678 | — |
Reaction Steps
A suspension of 30 g of 6-(4-chlorobutoxy)-carbostyril, 103 ml of benzylamine and 33 g of sodium iodide in 300 ml of dimethylformamide was stirred at 80° C. for 8 hours. The reaction mixture was allowed to cool and then poured into water. The resulting precipitate was collected by filtration. The precipitate was washed with water and diethyl ether in this order to obtain 29.1 g of 6-(4-benzylaminobutoxy)carbostyril.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05658926 |
|---|
| Source dataset | uspto-grants-1997_08 |
|---|
| ORD ID | ord-b4424247e90746e89c51de3cdacbf121 |
|---|
| Source note | uspto-grants-1997_08 |
|---|
