HCID 178487323, compound → HCID 178487324, compound

Participants

Reaction Steps

2.3 g (0.0095 mole) of 4-(6,7-dimethoxy-1H-inden-3-yl)-1H-imidazole prepared in Example 2.5.a in 200 ml of methanol are hydrogenated under a hydrogen pressure of 2 kg at 40° C., in the presence of palladium on carbon (Pd 10%). At the end of the reaction, the catalyst is filtered off and the methanol distilled. The residue is crystallized from ethyl acetate and 4-(2,3-dihydro-4,5-dimethoxy-1H-inden-1-yl)-1H-imidazole is obtained.

Provenance & Evidence