HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl tryptophanate hydrochloride → {3-[4-(Aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-L-tryptophan methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl tryptophanate hydrochloride | HCID 2734891 | — |
| Reactant | {3-[4-(Aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetic acid hydrochloride | HCID 67725476 | — |
| Product | {3-[4-(Aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-L-tryptophan methyl ester | HCID 67725084 | — |
Reaction Steps
403 mg of {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetic acid hydrochloride are coupled with 356.6 mg of L-tryptophan methyl ester hydrochloride by the process described above. After working up and chromatographic purification, 270 mg of {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-L-tryptophan methyl ester are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05658935 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-bee2b9cf96774dff826f9c69d08b8b96 |
| Source note | uspto-grants-1997_08 |