HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-amino-4-phenylbutanoate → {3-[4-(Aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-D,L-homophenylalanine methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-amino-4-phenylbutanoate | HCID 10856340 | — |
| Reactant | {3-[4-(Aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetic acid hydrochloride | HCID 67725476 | — |
| Product | {3-[4-(Aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-D,L-homophenylalanine methyl ester | HCID 131720120 | — |
Reaction Steps
403 mg of {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetic acid hydrochloride are coupled with 270 mg of D,L-homophenylalanine methyl ester by the process described above. After working up and chromatographic purification, 343 mg of {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}-acetyl-D,L-homophenylalanine methyl ester are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05658935 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-3f26847c2d1a4fae90761114ffb2b40b |
| Source note | uspto-grants-1997_08 |