HRID2257999

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN1C(=O)CC(Cc2ccc(C=NN)cc2)C1=O

HCID67725084

未命名化合物

PRODUCTS

生成物

结构：NN=Cc1ccc(CC2CC(=O)N(CC(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)O)C2=O)cc1

HCID67725592

未命名化合物

收率 34.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID313

Hydrochloric Acid

ClH

PROCEDURE

实验过程

204 mg of {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-L-tryptophan methyl ester are heated with 10 ml of 6N HCl for 3 min, then the mixture is evaporated to dryness and the residue is redistilled twice with water. The residue is taken up in a little water and freeze-dried. 68 mg of {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-L-tryptophan are obtained.

WORKUP

后处理

customthe mixture is evaporated to dryness
distillationthe residue is redistilled twice with water
customfreeze-dried