1-Bromopropane → HCID 178460919, compound

Participants

Reaction Steps

2.5 g (20 mmol) of n-propyl bromide was dripped into a mixture of 0.5 g of magnesium (21 mmol) and 50 ml of tetrahydrofuran (hereafter abbreviated as "THF") to obtain a Grignard's reagent. This solution was then dripped into a 50 ml THF solution of 6.1 g (20 mmol) of 4'-(4-chloro-4-silacyclohexyl)-4-fluorobiphenyl to obtain 4'-(trans-4-n-propyl-4-silacyclohexyl)-4-fluorobiphenyl.

Provenance & Evidence