Diisopropyl Ether → HCID 54506481, compound

HRID 2258313Notes

Reaction equation

[CH2:1]([C:11]1[CH:16]=[CH:15][C:14]([NH:17][C:18]([C:20]2[CH:21]=[C:22]([O:29][CH3:30])[C:23]([C:26]([OH:28])=O)=[N:24][CH:25]=2)=[O:19])=[CH:13][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].Cl.[CH2:32]([O:34][C:35](=[O:38])[CH2:36][NH2:37])[CH3:33].C(OC(C)C)(C)C>>[CH2:32]([O:34][C:35]([CH2:36][NH:37][C:26]([C:23]1[C:22]([O:29][CH3:30])=[CH:21][C:20]([C:18]([NH:17][C:14]2[CH:13]=[CH:12][C:11]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])=[CH:16][CH:15]=2)=[O:19])=[CH:25][N:24]=1)=[O:28])=[O:38])[CH3:33]

Participants

Reactant 3

HCID 7914Diisopropyl Ether

HCID 2723640Glycine ethyl ester, hydrochloride

HCID 22923777HCID 22923777, compound

Product 1

HCID 54506481HCID 54506481, compound

Procedure

5-(((4-n-Decylphenyl)amino)carbonyl)-3-methoxypyridine-2-carboxylic acid N-(ethoxycarbonylmethyl)amide was prepared from 5-(((-4-n-decylphenyl)amino)carbonyl)-3-methoxypyridine-2-carboxylic acid (m.p. 160° C., decomp.; from aqueous hydrochloric acid/THF) and glycine ethyl ester hydrochloride, m.p. 155°-157° C. (from diisopropyl ether).

Sources & evidence

ORD record: ord-b7e6720c2435421890a4691cfdf35317
Source dataset: uspto-grants-1997_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05658933

Reaction notes

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