HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → 3-[(2-Chloroacetyl)amino]-2,4,6-triiodobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | 3-Amino-2,4,6-triiodobenzoic acid | HCID 18387 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | 3-[(2-Chloroacetyl)amino]-2,4,6-triiodobenzoic acid | HCID 22921394 | 79% |
Reaction Steps
According to the procedure described in Example 1, a suspension of 103 g of 3-amino-2,4,6-triiodobenzoic acid (Beil. XIV, 414) (0.2 mol) in 200 ml of DMA is added to 24.8 g of chloroacetyl chloride (0.22 mol). 93.27 g of 3-[(2-chloroacetyl)amino]-2,4,6-triiodobenzoic acid are obtained (0.158 mol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05660814 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-fdc99b74eda645c0acb6968de1c590af |
| Source note | uspto-grants-1997_08 |