Water → HCID 12876556, compound

HRID 2258424Notes

Reaction equation

HRID 2258424 reaction equation
[C:1]1([S:7]([NH:10][C:11](=[O:21])[C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][CH:13]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.C(=O)([O-])[O-].[Na+].[Na+]>[Fe].C(O)(=O)C>[C:1]1([S:7]([NH:10][C:11](=[O:21])[C:12]2[CH:13]=[CH:14][C:15]([NH2:18])=[CH:16][CH:17]=2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

6

Reactant 3

HCID 962WaterHCID 10340Sodium CarbonateHCID 3826669Benzamide, 4-nitro-N-(phenylsulfonyl)-

Product 1

HCID 12876556HCID 12876556, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 176Acetic AcidSolvent

Procedure

27.2 g of the thus obtained N-(benzenesulfonyl)-p-nitrobenzamide, 270 g of water, and 5.4 g of glacial acetic acid were charged in a 1,000-ml reaction flask, 54 g of iron powder was slowly added, and a reductive reaction was carried out for 12 hours. The reaction solution was made alkaline with sodium carbonate and filtered. The transparent filtrate was acidified with acetic acid to obtain 19.8 g of N-(benzenesulfonyl)-p-aminobenzamide.

Workup

  1. additionwas slowly added
  2. customa reductive reaction
  3. filtrationfiltered

Sources & evidence

ORD record
ord-110b9d9f448c4d538c63d799088ecb67
Source dataset
uspto-grants-1997_08
Patent number
US05661100

Reaction notes

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