HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-chloro-N-[4-(4-pyridinyl)butyl]dibenz[b,f][1,4]oxazepine-10(11H)-carboxamide → 8-chloro-N-[4-(4-pyridinyl)butyl]dibenz[b,f][1,4]oxazepine-10(11H)-carboxamide, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-chloro-N-[4-(4-pyridinyl)butyl]dibenz[b,f][1,4]oxazepine-10(11H)-carboxamide | HCID 9801539 | — |
| Reactant | Hydrochloride methanol | HCID 21893726 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 8-chloro-N-[4-(4-pyridinyl)butyl]dibenz[b,f][1,4]oxazepine-10(11H)-carboxamide, hydrochloride | HCID 131720133 | 56.3% |
Reaction Steps
By the method described in Example 16, the title compound of Example 24 (0.82 g, 2.0 mmol) in 40 mL of MeOH was treated with 2N HCl/MeOH (5 mL) to produce 0.25 g of the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05661146 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-a483e195d5794c35a0ba19673b1a12c1 |
| Source note | uspto-grants-1997_08 |