反应详情

The title product of Example 18 (6.5 g, 13.4 mmol) dissolved in a mixture of EtOH and THF was hydrogenated in a standard Parr apparatus using-3% Pd on carbon as catalyst. The reaction was run under a H2 pressure of 5 psi for 5.5 hours at 40° C. to produce the crude product. This material was purified by HPLC on silica gel to yield 1.5 g of the title material.

1. customfor 5.5 hours
2. customat 40° C.
3. customto produce the crude product
4. customThis material was purified by HPLC on silica gel