Hydrochloric Acid → HCID 178437427, compound

Participants

Reaction Steps

To a mixture of 2-ethyl-5,7-dimethyl-3-[4-[1-ethyl-5-methyl-3-(1H-tetrazol-5-yl)pyrrol-2-yl]benzyl]-3H-imidazo-[4,5-b]pyridine (3.54 g) and ethanol (18 ml) was added 12N hydrochloric acid (0.8 ml), and the reaction mixture was heated in a boiling bath for a few minutes. The resultant solution was evaporated in vacuo, and the residue was crystallized from a mixture of 1N hydrochloric acid and ethanol to afford 2-ethyl-5,7-dimethyl-3-[4-[1-ethyl-5-methyl-3-(1H-tetrazol-5-yl)pyrrol-2-yl]benzyl]-3H-imidazo-[4,5-b]pyridine hydrochloride (2.38 g). m.p. 246°-248° C.

Provenance & Evidence