HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus tribromide → 1-(Bromomethyl)-2,4-dimethoxybenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus tribromide | HCID 24614 | — |
| Reactant | 2,4-Dimethoxybenzyl alcohol | HCID 81750 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-(Bromomethyl)-2,4-dimethoxybenzene | HCID 15151907 | — |
Reaction Steps
A solution of 0.537 g of 1-hydroxymethyl-2,4-dimethoxybenzene in 5 ml of ether is cooled to -10° C., under a nitrogen atmosphere, and a solution of 0.1 ml of phosphorus tribromide in 2 ml of ether is added dropwise. The 1-bromomethyl-2,4-dimethoxybenzene thus obtained is stored in solution at -30° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05661169 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-11cd3f241c7b471c9b9999aabac0fdb2 |
| Source note | uspto-grants-1997_08 |