HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 19003217, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Chlorobenzenesulfonyl chloride | HCID 7398 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 178479278 | HCID 178479278 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 19003217 | HCID 19003217 | 95% |
Reaction Steps
To 100 g of trans-4-aminocyclohexanol hydrochloride suspended in 11 of chloroform are added, at 5° C., 184 ml of triethylamine, followed by a solution containing 143 g of 4-chlorophenylsulfonyl chloride in 150 ml of chloroform. After reaction for 2 hours, the reaction mixture is poured onto 500 ml of water. The expected product is obtained by filtration of the precipitate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05472979 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-bc1ec3e45362478b88e4c84a40c5c387 |
| Source note | uspto-grants-1995_12 |