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HRID2259284

反应详情

EQUATION

反应方程式

HRID 2259284 的结构方程式

REACTANTS

反应物

2
结构：COc1ccccc1CCl
HCID81495

2-(Chloromethyl)anisole

C8H9ClO

结构：CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O
HCID83169

L-Tryptophan, N-[(1,1-dimethylethoxy)carbonyl]-

C16H20N2O4

PRODUCTS

生成物

1
结构：COc1ccccc1COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
HCID19003118

未命名化合物

PROCEDURE

实验过程

Following the method of Example 1, 2-methoxybenzyl chloride (3.9) and N α BOC-L-tryptophan (7.6 g) gave the title compound which was recrystallised from ethyl acetate/petroleum ether (3.4 g), m.p. 132°-133° C. 1H NMR (360 MHz, CDCl3) δ7.99 (1H, s), 7.56 (1H, d, J=Hz), 7.33-7.07 (5H, m), 6.93-6.66 (3H, m), 5.21-5.07 (3H, m), 4.70-4.67 (1H, m), 3.01 (3H, s), 3.30 (1H, m), 1.41 (9H, s). Found: C, 67.91; H, 6.65; N, 6.60; C24H28N2O5 requires C, 68.00; H, 6.70; N, 6.66%.