Hydrogen Peroxide → Acetophenone

HRID 2259463Notes

Reaction equation

HRID 2259463 reaction equation
[C:1]1([CH:7]([CH3:9])[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH:10]O>>[C:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:10])[CH3:9].[C:1]1([C:7]([OH:10])([CH3:9])[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 7406Cumene2×

Product 2

HCID 7410AcetophenoneYield 43.1%HCID 120532-Phenyl-2-propanolYield 30.6%

Procedure

The procedure of Example III was repeated, but this time cumene (0.056 moles) and hydrogen peroxide (35%, 0.22 moles) were used. The reaction mixture, analysed by HPLC, revealed that 87.4% of the cumene had been consumed, yielding products including acetophenone (43.1% yield) and 2-phenyl-2-propanol (30.6% yield).

Workup

  1. customhad been consumed
  2. customyielding products

Sources & evidence

ORD record
ord-547c335ee50e467486ad66929307b752
Source dataset
uspto-grants-1995_12
Patent number
US05473101

Reaction notes

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