HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2,3-Dichlorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Benzene, 1,2-dichloro-3-methyl- | HCID 34702 | — |
| Reactant | Sodium Bromide | HCID 253881 | — |
| Catalyst | Cobalt(II) acetate tetrahydrate | HCID 61372 | — |
| Product | 2,3-Dichlorobenzoic acid | HCID 5765 | 23.8% |
| Product | 2,3-Dichlorobenzaldehyde | HCID 35745 | 15.2% |
Reaction Steps
The procedure of Example I was repeated, but this time cobalt (II) acetate tetrahydrate (0.012 moles), sodium bromide (0.05 moles), dichlorotoluene (0.074 moles), acetic acid (100 g) and hydrogen peroxide (70%, 0.68 moles) were used and the reaction was performed at 90° C. for three hours. The final reaction mixture, analysed by HPLC, revealed that 66.0% of the dichlorotoluene had been consumed, yielding products including dichlorobenzaldehyde (15.2% yield) and dichlorobenzoic acid (23.8% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05473101 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-2f3c76ec3bdf4706a3d7f16e909691e8 |
| Source note | uspto-grants-1995_12 |